Contact Lens Registry Examination (CLRE) Practice

The correct order of the layers of the cornea from outside to inside is the epithelium, Bowman's layer, stroma, Descemet's membrane, and endothelium.

Starting with the epithelium, this is the outermost layer that serves as a protective barrier against environmental factors. It is vital for maintaining corneal integrity and plays a role in sensation due to the rich nerve supply.

Beneath the epithelium lies Bowman's layer, which provides additional structural support and helps maintain the shape and transparency of the cornea. This layer is composed of collagen fibers and is distinct from the stroma, which is the thickest layer of the cornea. The stroma accounts for about 90% of the corneal thickness and is made up of tightly packed collagen fibers that give the cornea its strength and clarity.

Next is Descemet's membrane, a thin but strong layer that acts as a basement membrane for the endothelium. It contributes to the overall barrier function of the cornea and helps to maintain corneal shape.

Finally, the innermost layer is the endothelium, which is responsible for maintaining corneal hydration and transparency. It regulates the amount of fluid in